1950s. In the border town of La Frontera, young love blooms at first sight between Fulgencio Ramirez, the son of impoverished immigrants, and Carolina Mendelssohn, the local pharmacist's daughter. Their bonds will be undone by a force more powerful than they could have known. Thirty years later Fulgencio Ramirez, RPh, is conducting his daily ritual of reading the local obituaries in his pharmacy office. After nearly a quarter of a century of waiting, his nemesis, the husband of Carolina Mendelssohn, has died. Fulgencio strives to succeed in America, break a mystical family curse, and win back Carolina's love after their doomed youthful romance.